Article
PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.
The EMBO journal - 17 Oct 1994
Marzioch M, Erdmann R, Veenhuis M, Kunau W H
Abstract excerpt
To identify components of the peroxisomal import pathway in yeast, we have isolated pas mutants affected in peroxisome biogenesis. Two mutants assigned to complementation group 7 define a new gene, PAS7, whose product is necessary for import of thiolase, a PTS2-containing protein, but not for tha...
Topics
- Acetyl-CoA C-Acyltransferase
- Amino Acid Sequence
- Base Sequence
- Biological Transport
- Cell Adhesion Molecules
- Cloning, Molecular
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Microbodies
- Molecular Sequence Data
- Mutation
- Peroxisomal Targeting Signal 2 Receptor
- Receptors, Cytoplasmic and Nuclear