Article
CD8+ T lymphocytes protect SCID mice against Encephalitozoon cuniculi infection.
International journal for parasitology - 15 May 2001
Braunfuchsová P, Salát J, Kopecký J
Abstract excerpt
Microsporidia are obligate intracellular parasites that cause opportunistic infections in immunocompromised patients. The role of two main T cell subsets in anti-microsporidial immunity has been studied using an Encephalitozoon cuniculi-severe combined immunodeficient (SCID) mouse model. Whereas SCID mice reconstituted with CD4+ T lymphocyte-depleted naive BALB/c splenocytes resolved the infection, adoptive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
