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Article

Cytoskeletal effects induced by pet, the serine protease enterotoxin of enteroaggregative Escherichia coli.

Infection and immunity - 1 May 1999

Navarro-García F, Sears C, Eslava C, Cravioto A, Nataro J P

Abstract excerpt

We have previously described enteroaggregative Escherichia coli (EAEC) strains that induce cytotoxic effects on T84 cells, ligated rat ileal loops, and human intestine in culture. Such strains secrete a 104-kDa protein termed Pet (for plasmid-encoded toxin). We have also shown previously that the Pet toxin induces rises in short-circuit current and decreases the electrical resistance in rat jejunum mounted in an...

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Identifiers

PMID: 10225873
DOI: 10.1128/IAI.67.5.2184-2192.1999
PMCID: PMC115956

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