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Article

Involvement of the Enteroaggregative <i>Escherichia coli</i> Plasmid-Encoded Toxin in Causing Human Intestinal Damage

1 Oct 1999

Abstract excerpt

Enteroaggregative Escherichia coli (EAEC) strains have been shown to adhere to human intestinal tissue in an in vitro organ culture (IVOC) model, and certain strains manifest mucosal toxicity. We have recently described the EAEC plasmid-encoded toxin (Pet), a member of a specific serine protease subclass of the autotransporter proteins. When injected into rat ileal loops, Pet both elicited fluid accumulation and...

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Identifiers

PMID: 10496914
DOI: 10.1128/iai.67.10.5338-5344.1999

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