Article
Mutant alleles of the Drosophila trithorax gene produce common and unusual homeotic and other developmental phenotypes.
Genetics - 1 May 1999
Breen T R
Abstract excerpt
trithorax (trx) encodes chromosome-binding proteins required throughout embryogenesis and imaginal development for tissue- and cell-specific levels of transcription of many genes including homeotic genes of the ANT-C and BX-C. trx encodes two protein isoforms that contain conserved motifs including a C-terminal SET domain, central PHD fingers, an N-terminal DNA-binding homology, and two short motifs also found in...
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