Article
Mitochondrial superoxide decreases yeast survival in stationary phase.
Archives of biochemistry and biophysics - 1 May 1999
Longo V D, Liou L L, Valentine J S, Gralla E B
Abstract excerpt
Yeast lacking mitochondrial superoxide dismutase (MnSOD) display shortened stationary-phase survival and provide a good model system for studying mitochondrial oxidative damage. We observed a marked decrease in respiratory function preceding stationary-phase death of yeast lacking MnSOD (sod2Delta). Agents (mitochondrial inhibitors) that are known to increase or decrease superoxide production in submitochondrial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
