Article
Glutathione reductase activity deficiency in homozygous Gr1a1Neu mice does not cause haemolytic anaemia.
Genetical research - 1 Feb 1999
Pretsch W
Abstract excerpt
A glutathione reductase (GR) mutant with approximately 50% residual enzyme activity in blood compared with wild-type was detected amongst offspring of isopropyl methanesulphonate-treated male mice. Homozygous mutants with only 2% residual enzyme activity were recovered in progeny of inter se matings of heterozygotes. Results of linkage studies indicate a mutation at the Gr1 structural locus on chromosome 8. The...
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