A glucosephosphate isomerase (GPI) null mutation in Mus musculus: evidence that anaerobic glycolysis is the predominant energy delivering pathway in early post-implantation embryos.

doi:10.1016/0305-0491(92)90004-b

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Article

A glucosephosphate isomerase (GPI) null mutation in Mus musculus: evidence that anaerobic glycolysis is the predominant energy delivering pathway in early post-implantation embryos.

Comparative biochemistry and physiology. B, Comparative biochemistry - 1 Mar 1992

Merkle S, Pretsch W

Abstract excerpt

1. A heterozygous mouse mutant exhibiting approximately 50% of wild-type glucose-6-phosphate isomerase (GPI) activity in blood was recovered in mutagenicity experiments after combined treatment of spermatogonia with triethylenemelamine and irradiation. 2. Biochemical and immunological studies rev...

Topics

Anaerobiosis
Animals
Embryonic Development
Energy Metabolism
Erythrocytes
Female
Fetal Death
Glucose-6-Phosphate Isomerase
Glycolysis
Homozygote
Kinetics
Male
Mice
Mutation
Pregnancy

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PMID: 1582174
DOI: 10.1016/0305-0491(92)90004-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1582174-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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