Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early growth determines longevity in male rats and may be related to telomere shortening in the kidney

1 Apr 1999

Abstract excerpt

Maternal protein undernutrition can influence the growth and longevity of male offspring in the rat. We tested the hypothesis that these differences in longevity were associated with changes in the rate of telomere shortening. We found age-related shortening of telomeres in the liver and kidney but not in the brain of male rats. Growth retardation in postnatal life was associated with significantly longer kidney...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10217398
DOI: 10.1016/s0014-5793(99)00336-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early growth determines longevity in male rats and may be related to telomere shortening in the kidneyPMID 10217398Read ↗

Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expressionSemantic proximity Read ↗

Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shorteningSemantic proximity Read ↗

Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat isletsSemantic proximity Read ↗

Maternal Low-Protein Diet Impairs Prostate Growth in Young Rat Offspring and Induces Prostate Carcinogenesis With AgingSemantic proximity Read ↗

Genes that prolong life: relationships of growth hormone and growth to aging and life span.Semantic proximity Read ↗

An Extensive Genetic Program Occurring during Postnatal Growth in Multiple TissuesSemantic proximity Read ↗

Telomere Shortening in Kidneys with AgeSemantic proximity Read ↗

Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.Semantic proximity Read ↗

Longevity is impacted by growth hormone action during early postnatal period.Semantic proximity Read ↗

Prenatal Exposure to a Maternal Low Protein Diet Shortens Life Span in RatsSemantic proximity Read ↗

Somatotropic Axis, Pace of Life and AgingSemantic proximity Read ↗

Growth hormone actions during development influence adult phenotype and longevity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.