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Identification and characterization of a serine hydroxymethyltransferase isoform in Caenorhabditis briggsae.

Gene - 16 Apr 1999

Vatcher G P, Barbazuk W B, O'Neil N J, Marra M A, Ha T, Baillie D L

Abstract excerpt

In the nematode Caenorhabditis elegans, the maternal effect lethal gene mel-32 encodes a serine hydroxymethyltransferase isoform. Since interspecies DNA comparison is a valuable tool for identifying sequences that have been conserved because of their functional importance or role in regulating gene activity, mel-32(SHMT) genomic DNA from C. elegans was used to screen a genomic library from the closely related...

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PMID: 10216251
DOI: 10.1016/s0378-1119(99)00076-1

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