Article
The novel sarcomeric protein telethonin exhibits developmental and functional regulation.
Biochemical and biophysical research communications - 21 Apr 1999
Mason P, Bayol S, Loughna P T
Abstract excerpt
We have isolated a cDNA clone from a mouse skeletal muscle library which is preferentially expressed in striated muscle and exhibits a high homology to human telethonin, a sarcomeric protein. The mouse telethonin transcript is developmentally regulated in both cardiac and skeletal muscle in vivo and is down-regulated in response to denervation. In the C2C12 muscle cell-line the mouse telethonin transcript...
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