Article
pH-Responsive, posttranslational regulation of the Trk1 potassium transporter by the type 1-related Ppz1 phosphatase.
Molecular and cellular biology - 1 Oct 2005
Yenush Lynne, Merchan Stephanie, Holmes James, Serrano Ramón
Abstract excerpt
Intracellular pH and K+ concentrations must be tightly controlled because they affect many cellular activities, including cell growth and death. The mechanisms of homeostasis of H+ and K+ are only partially understood. In the yeast Saccharomyces cerevisiae, proton efflux is mediated by the Pma1 H+-ATPase. As this pump is electrogenic, the activity of the Trk1 and -2 K+ uptake system is crucial for sustained Pma1p...
Topics
- Biological Transport
- Cation Transport Proteins
- Cell Membrane
- Dose-Response Relationship, Drug
- Genotype
- Green Fluorescent Proteins
- Homeostasis
- Hydrogen-Ion Concentration
- Immunoprecipitation
- Membrane Microdomains
- Microscopy, Fluorescence
- Mutation
- Phosphoprotein Phosphatases