Article
Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 13 Apr 1999
Duret L, Mouchiroud D
Abstract excerpt
We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917 genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and Arabidopsis thaliana. In those three species, we observed a clear correlation between codon usage and gene expression levels and showed that this correlation is not due to a mutational bias. This provides direct evidence for selection on silent sites...
Topics
- Animals
- Arabidopsis
- Biological Evolution
- Caenorhabditis elegans
- Codon
- Drosophila melanogaster
- Expressed Sequence Tags
- Gene Expression Regulation
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Plant
- Mutation
- RNA, Messenger
- Selection, Genetic