Article
Mitotic control in the absence of cdc25 mitotic inducer in fission yeast.
Journal of cell science - 1 Apr 1999
Sveiczer A, Novak B, Mitchison J M
Abstract excerpt
Fission yeast cells tolerate the total absence of the cdc25 mitotic inducer in two cases, either in cdc2-3w or in wee1 genetic backgrounds. In the cdc2-3w cdc25Delta double mutant, the rate-limiting step leading to mitosis is reaching a critical size. However, the size control of this mutant operates in late G2, which is different from wild-type (WT) cells. This fact suggests that in WT the rate-limiting...
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