Article
Genetic polymorphism of the angiotensin-converting enzyme (ACE) in asthmatic patients.
Respiratory medicine - 1 Dec 1998
Tomita H, Sato S, Matsuda R, Ogisu N, Mori T, Niimi T, Shimizu S
Abstract excerpt
Angiotensin-converting enzyme (ACE) inactivates bradykinin, substance P and neurokinin A, which are believed to play important roles in the pathogenesis of asthma, especially in neurogenic inflammation. It has recently been shown that an insertion (I)/deletion (D) polymorphism in the ACE gene acc...
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