Article
Polymorphism of angiotensin-converting enzyme gene and genetic susceptibility to asthma with familial aggregation.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Mar 2000
Gao J, Lin Y, Xiao Y, Xu K, Xu W, Zhu Y, Ma Y, Bai Y
Abstract excerpt
OBJECTIVE: Angiotensin-converting enzyme (ACE) plays a key role in the metabolism of angiotensin II (AT II) and inactivation of bradykinins and tachykinins, which are potent bronchialconstrictors and mediators of inflammation asthma, and ACE is heavily expressed in the lungs. An insertion-deletio...
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