Article
Association between angiotensin-converting enzyme gene polymorphism and childhood allergic rhinitis in Taiwan.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Aug 2006
Ku Min-Sho, Lue Ko-Huang, Li Ching, Sun Hai-Lun, Chou Ming-Chih
Abstract excerpt
BACKGROUND AND PURPOSE: Angiotensin-converting enzyme (ACE) play a role in inactivating bradykinin and tachykinins. Bradykinin and tachykinins are potent mediators of inflammatory reaction. An insertion/deletion polymorphism of the ACE gene has been shown to be associated with serum ACE levels. We hypothesized that ACE polymorphism might play a role in allergic rhinitis development. METHODS: Seventy five children...
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