Article
Bystander Target Cell Lysis and Cytokine Production by Dengue Virus-Specific Human CD4+Cytotoxic T-Lymphocyte Clones
1 May 1999
Abstract excerpt
Dengue hemorrhagic fever, the severe form of dengue virus infection, is believed to be an immunopathological response to a secondary infection with a heterologous serotype of dengue virus. Dengue virus capsid protein-specific CD4(+) cytotoxic T-lymphocyte (CTL) clones were shown to be capable of mediating bystander lysis of non-antigen-presenting target cells. After activation by anti-CD3 or in the presence of...
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