Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Partial Agonist Effect Influences the CTL Response to a Heterologous Dengue Virus Serotype

1 Sept 1999

Abstract excerpt

Activation of dengue serotype-cross-reactive memory CTL during secondary dengue virus (DV) infection is thought to be important in the pathogenesis of dengue hemorrhagic fever. To model this effect, we studied the CTL responses to DV types 2 (D2V) and 3 (D3V) in PBMC from an individual previously infected with D3V. DV-specific CD8+ CTL from this donor recognized two HLA-B62-restricted epitopes on the NS3 protein,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mosquito-borne diseases and control
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10453018
DOI: 10.4049/jimmunol.163.5.2754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Partial Agonist Effect Influences the CTL Response to a Heterologous Dengue Virus SerotypePMID 10453018Read ↗

Dengue virus-reactive CD8+ T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes.Semantic proximity Read ↗

Immunodominance Changes as a Function of the Infecting Dengue Virus Serotype and Primary versus Secondary InfectionSemantic proximity Read ↗

Differential Functional Avidity of Dengue Virus-Specific T-Cell Clones for Variant Peptides Representing Heterologous and Previously Encountered SerotypesSemantic proximity Read ↗

Induction of T lymphocyte responses to dengue virus by a candidate tetravalent live attenuated dengue virus vaccine.Semantic proximity Read ↗

Dengue virus-specific, HLA-B35-restricted, human CD8+ cytotoxic T lymphocyte (CTL) clones. Recognition of NS3 amino acids 500 to 508 by CTL clones of two different serotype specificities.Semantic proximity Read ↗

Cross‐Reactive Memory CD8+T Cells Alter the Immune Response to Heterologous Secondary Dengue Virus Infections in Mice in a Sequence‐Specific MannerSemantic proximity Read ↗

Predominance of HLA-Restricted Cytotoxic T-Lymphocyte Responses to Serotype-Cross-Reactive Epitopes on Nonstructural Proteins following Natural Secondary Dengue Virus InfectionSemantic proximity Read ↗

Dengue virus-specific, human CD4+ CD8- cytotoxic T-cell clones: multiple patterns of virus cross-reactivity recognized by NS3-specific T-cell clonesSemantic proximity Read ↗

Dengue Virus Directly Stimulates Polyclonal B Cell Activation.Semantic proximity Read ↗

Definition of an HLA-DPw2-restricted epitope on NS3, recognized by a dengue virus serotype-cross-reactive human CD4+ CD8- cytotoxic T-cell clone.Semantic proximity Read ↗

T Lymphocyte Responses to Heterologous Secondary Dengue Virus InfectionsSemantic proximity Read ↗

Flavivirus-cross-reactive, HLA-DR15-restricted epitope on NS3 recognized by human CD4+ CD8- cytotoxic T lymphocyte clonesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.