Article
Lower activation-induced T-cell apoptosis is related to the pathological immune response in secondary infection with hetero-serotype dengue virus.
Immunobiology - 1 Mar 2016
Yang Wang, Yan Huacheng, Ma Yuling, Yu Tiantian, Guo Hongxia, Kuang Yuchan, Ren Ruiwen, Li Jintao
Abstract excerpt
The available evidence suggests that dengue virus-specific T lymphocytes and cytokine storm play a pivotal role in the immunopathogenesis of plasma leakage. Investigations are underway to identify the immune profiles associated with increased or decreased risk for severe disease. In this study, CD14+ cells from the peripheral blood mononuclear cells (PBMCs) of patients who recovered from DENV-1 infection were...
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