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Article

Normal respiratory mucosa, precursor lesions and lung carcinomas: differential expression of human mucin genes

1 Jan 2001

Abstract excerpt

Mucins are glycoproteins synthesized by epithelial cells and thought to promote tumor-cell invasion. Eight human mucin genes have been well characterized: MUC2, MUC5AC, MUC5B, MUC6 map to 11p15.5 and encode secretory gel forming mucins while MUC1, MUC3, MUC4, MUC7 are scattered on different chromosomes and encode membrane-bound or secreted mucins. The expression pattern of the mucin genes is complex in normal...

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PMID: 11578957
DOI: 10.2741/copin

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