Article
Presence of multiple functional polyadenylation signals and a single nucleotide polymorphism in the 3' untranslated region of the human serotonin transporter gene.
Journal of neurochemistry - 1 Apr 1999
Battersby S, Ogilvie A D, Blackwood D H, Shen S, Muqit M M, Muir W J, Teague P, Goodwin G M, Harmar A J
Abstract excerpt
The human serotonin transporter (hSERT) gene is a candidate for involvement in the aetiology of affective disorders. In humans, multiple transcripts of the gene have been detected by northern blot analysis of brain and other tissues. We performed 3' rapid amplification of cDNA ends to identify the common sites of polyadenylation in hSERT mRNA from human JAR cells and whole blood. Two major polyadenylation sites...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.