Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is Gonadotrope Expression of the Gonadotropin Releasing Hormone Receptor Gene Mediated by Autocrine/Paracrine Stimulation of an Activin Response Element?

1 Apr 1999

Abstract excerpt

Expression of the FSHbeta subunit and GnRH receptor (GnRHR) genes in gonadotropes is stimulated by activin. We sought to identify the cis-acting element(s) in the murine GnRHR gene promoter which confer activin responsiveness. We established that 600 bp of 5'flanking sequence from the murine GnRHR gene were sufficient to confer activin responsiveness in the gonadotrope-derived alphaT3-1 cell line. Since alphaT3-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10098536
DOI: 10.1210/endo.140.4.6780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is Gonadotrope Expression of the Gonadotropin Releasing Hormone Receptor Gene Mediated by Autocrine/Paracrine Stimulation of an Activin Response Element?PMID 10098536Read ↗

Homologous Regulation of the Gonadotropin-Releasing Hormone Receptor Gene Is Partially Mediated by Protein Kinase C Activation of an Activator Protein-1 ElementSemantic proximity Read ↗

Steroidogenic Factor-1 Interacts with a Gonadotrope-Specific Element within the First Exon of the Human Gonadotropin-Releasing Hormone Receptor Gene to Mediate Gonadotrope-Specific Expression*Semantic proximity Read ↗

Activin A Augments GnRH-Mediated Transcriptional Activation of the Mouse GnRH Receptor GeneSemantic proximity Read ↗

The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein.Semantic proximity Read ↗

Welcoming β-Catenin to the Gonadotropin-Releasing Hormone Transcriptional Network in GonadotropesSemantic proximity Read ↗

Stimulation of luteinizing hormone beta gene promoter activity by the orphan nuclear receptor, steroidogenic factor-1.Semantic proximity Read ↗

Nuclear Factor Y and Steroidogenic Factor 1 Physically and Functionally Interact to Contribute to Cell-Specific Expression of the Mouse Follicle-Stimulating Hormone-β GeneSemantic proximity Read ↗

Follistatin suppresses FSHβ but increases LHβ expression in the goldfish – evidence for an activin-mediated autocrine/paracrine system in fish pituitarySemantic proximity Read ↗

Oct-1 and nuclear factor Y bind to the SURG-1 element to direct basal and gonadotropin-releasing hormone (GnRH)-stimulated mouse GnRH receptor gene transcription.Semantic proximity Read ↗

Transcript Profiling of Immediate Early Genes Reveals a Unique Role for Activating Transcription Factor 3 in Mediating Activation of the Glycoprotein Hormone α-Subunit Promoter by Gonadotropin-Releasing HormoneSemantic proximity Read ↗

Steroidogenic factor-1 and the gonadotrope-specific element enhance basal and pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein hormone alpha-subunit gene in gonadotropes.Semantic proximity Read ↗

Synergy between activin A and gonadotropin-releasing hormone in transcriptional activation of the rat follicle-stimulating hormone-beta gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.