Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of Cytotrophoblast Columns from Explanted First-Trimester Human Placental Villi: Role of Fibronectin and Integrin α5β11

1 Apr 1999

Abstract excerpt

Human first-trimester floating mesenchymal villi explanted onto gels of collagen I or Matrigel were observed to undergo de novo development of anchoring sites. These consisted of cytotrophoblast columns that formed by proliferation of stem villous cytotrophoblast cells, as revealed by whole-mount and thin-section microscopy and incorporation of bromodeoxyuridine into DNA. Column formation occurred exclusively at...

Source

Identifiers

PMID: 10084955
DOI: 10.1095/biolreprod60.4.828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of Cytotrophoblast Columns from Explanted First-Trimester Human Placental Villi: Role of Fibronectin and Integrin α5β11PMID 10084955Read ↗

Trophoblast differentiation during formation of anchoring villi in a model of the early human placenta in vitro.Semantic proximity Read ↗

Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.Semantic proximity Read ↗

Developmental cell biology of human villous trophoblast: current research problemsSemantic proximity Read ↗

Endoglin Regulates Trophoblast Differentiation along the Invasive Pathway in Human Placental Villous Explants*Semantic proximity Read ↗

Characteristics of trophoblast cells migrating from first trimester chorionic villus explants and propagated in culture.Semantic proximity Read ↗

Extracellular Matrix Composition and Hypoxia Regulate the Expression of HLA-G and Integrins in a Human Trophoblast Cell Line1Semantic proximity Read ↗

Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotypeSemantic proximity Read ↗

Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?Semantic proximity Read ↗

Isolation and characterization of human placental trophoblast subpopulations from first-trimester chorionic villiSemantic proximity Read ↗

Insulin-like growth factor I and II regulate the life cycle of trophoblast in the developing human placentaSemantic proximity Read ↗

Cytotrophoblast differentiation in the first trimester of pregnancy: evidence for separate progenitors of extravillous trophoblasts and syncytiotrophoblastSemantic proximity Read ↗

Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.