Article
Trophoblast differentiation during formation of anchoring villi in a model of the early human placenta in vitro.
Placenta - 1 Jan 1995
Vićovac L, Jones C J, Aplin J D
Abstract excerpt
In human implantation sites, formation of the cytotrophoblast shell and morphogenesis of anchoring villi occur during the 2nd and 3rd week of pregnancy. When placental villous tissue from 8-12 weeks was co-cultured with decidua parietalis, morphogenetic changes were observed specifically at sites of heterotypic contact, generating structures that closely resembled first trimester anchoring villi. Local breakdown...
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