Article
Residue 3 of beta2-microglobulin affects binding of class I MHC molecules by the W6/32 antibody.
Immunogenetics - 1 Apr 1999
Ladasky J J, Shum B P, Canavez F, Seuánez H N, Parham P
Abstract excerpt
Previous studies of class I MHC molecules have shown that the owl monkey (Aotus) possesses at least two variants of the beta2-microglobulin (beta2m) protein. These two variants have different isoelectric points, and exhibit differential reactivity with the monoclonal antibody W6/32. We report cDNA sequences of the B2m gene, from W6/32-positive and W6/32-negative Aotus cell lines. The two beta2m variants we...
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