Analysis of TFIIH subunit through isolation of the gene from Schizosaccharomyces pombe corresponding to that of Saccharomyces cerevisiae SSL1, reveals the presence of conserved structural motifs.

Abstract excerpt

We isolated a Schizosaccharomyces pombe (Sz. pombe) gene encoding the counterpart of the TFIIH subunit Homo sapiens (H. sapiens) p44 and Saccharomyces cerevisiae (S. cerevisiae) SSL1, and we named this gene product p47. Contrary to the case of SSL1, which is an essential gene of S. cerevisiae, p4...

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