Two Germline Missense Mutations at Codons 804 and 806 of the <i>RET</i> Proto‐oncogene in the Same Allele in a Patient with Multiple Endocrine Neoplasia Type 2B without Codon 918 Mutation

doi:10.1111/j.1349-7006.1999.tb00658.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Two Germline Missense Mutations at Codons 804 and 806 of the <i>RET</i> Proto‐oncogene in the Same Allele in a Patient with Multiple Endocrine Neoplasia Type 2B without Codon 918 Mutation

1 Jan 1999

Abstract excerpt

Multiple endocrine neoplasia (MEN) type 2B is a clinically distinct entity among the autosomal dominant MEN 2 syndromes. Most patients with MEN 2B carry a germline mutation (M918T) of the RET proto-oncogene, while a few carry A883F. We examined a patient with MEN 2B, but without M918T or A883F, and her relatives. Here, we report the presence in this patient of 2 germline mutations, V804M and Y806C in the same...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Neuroendocrine Tumor Research Advances
Share to Thyroid Cancer Diagnosis and Treatment

Source

Open in PubMed

Identifiers

PMID: 10076558
DOI: 10.1111/j.1349-7006.1999.tb00658.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics