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Article

Germline Dinucleotide Mutation in Codon 883 of the<i>RET</i>Proto-Oncogene in Multiple Endocrine Neoplasia Type 2B Without Codon 918 Mutation

1 Nov 1997

Abstract excerpt

The autosomal dominant multiple endocrine neoplasia type 2 syndromes (MEN 2) comprise three clinically distinct entities, MEN 2A, familial medullary thyroid carcinoma and MEN 2B, which share a common clinical feature: medullary thyroid carcinoma (MTC). MEN 2B is considered to have the most aggressive form of MTC. Therefore, early detection of MEN 2B in order to prevent potentially lethal MTC is important. More...

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Identifiers

PMID: 9360560
DOI: 10.1210/jcem.82.11.4508

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Germline Dinucleotide Mutation in Codon 883 of the<i>RET</i>Proto-Oncogene in Multiple Endocrine Neoplasia Type 2B Without Codon 918 MutationPMID 9360560Read ↗

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