Article
Germline BRCA1 promoter deletions in UK and Australian familial breast cancer patients: Identification of a novel deletion consistent with BRCA1:psiBRCA1 recombination.
Human mutation - 1 Apr 2002
Brown Melissa A, Lo Li-Jan, Catteau Aurélie, Xu Chun-Fang, Lindeman Geoffrey J, Hodgson Shirley, Solomon Ellen
Abstract excerpt
Inherited susceptibility to breast cancer results from germline mutations in one of a number of genes including BRCA1. A significant number of BRCA1-linked familial breast cancer patients, however, have no detectable BRCA1 mutation. This could be due in part to the inability of commonly used mutation-detection techniques to identify mutations outside the BRCA1 coding region. This paper addresses the hypothesis...
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