Article
Polymorphism T-->C (-34 bp) of gene CYP17 promoter in Greek patients with polycystic ovary syndrome.
Fertility and sterility - 1 Mar 1999
Diamanti-Kandarakis E, Bartzis M I, Zapanti E D, Spina G G, Filandra F A, Tsianateli T C, Bergiele A T, Kouli C R
Abstract excerpt
OBJECTIVE: To investigate the frequency of T-->C substitution (-34 bp) of gene CYP17 promoter in Greek patients with polycystic ovary syndrome (PCOS) and to elucidate its role in the pathogenesis of the syndrome. DESIGN: Follow-up study. SETTING: Academic research setting. PATIENT(S): Fifty patients with PCOS and 50 healthy women. INTERVENTION(S): Body mass index and the waist-hip ratio were determined for each...
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