Article
Acetylcholine-induced relaxation in blood vessels from endothelial nitric oxide synthase knockout mice.
British journal of pharmacology - 1 Jan 1999
Chataigneau T, Félétou M, Huang P L, Fishman M C, Duhault J, Vanhoutte P M
Abstract excerpt
1. Isometric tension was recorded in isolated rings of aorta, carotid, coronary and mesenteric arteries taken from endothelial nitric oxide synthase knockout mice (eNOS(-/-) mice) and the corresponding wild-type strain (eNOS(+/+) mice). The membrane potential of smooth muscle cells was measured in coronary arteries with intracellular microelectrodes. 2. In the isolated aorta, carotid and coronary arteries from...
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