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Article

Relationship between UDP-glucose 4-epimerase activity and oligoglucose glycoforms in two strains of Neisseria meningitidis.

Infection and immunity - 1 Mar 1999

Lee F K, Gibson B W, Melaugh W, Zaleski A, Apicella M A

Abstract excerpt

Sodium dodecyl sulfate-polyacrylamide gel analysis of lipooligosaccharide (LOS) from Neisseria meningitidis has demonstrated considerable microheterogeneity in the variable region of LOS due to the presence of novel glycoforms. As a step toward understanding the basis for the expression of these novel glycoforms, we have examined the LOS structures and UDP-glucose 4-epimerase (epimerase) activity levels in two...

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Identifiers

PMID: 10024588
DOI: 10.1128/IAI.67.3.1405-1414.1999
PMCID: PMC96474

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