Article
Relationship between UDP-glucose 4-epimerase activity and oligoglucose glycoforms in two strains of Neisseria meningitidis.
Infection and immunity - 1 Mar 1999
Lee F K, Gibson B W, Melaugh W, Zaleski A, Apicella M A
Abstract excerpt
Sodium dodecyl sulfate-polyacrylamide gel analysis of lipooligosaccharide (LOS) from Neisseria meningitidis has demonstrated considerable microheterogeneity in the variable region of LOS due to the presence of novel glycoforms. As a step toward understanding the basis for the expression of these novel glycoforms, we have examined the LOS structures and UDP-glucose 4-epimerase (epimerase) activity levels in two...
Topics
- Amino Acid Sequence
- Blotting, Western
- Lipopolysaccharides
- Mass Spectrometry
- Molecular Sequence Data
- Mutation
- Neisseria meningitidis
- Oligosaccharides
- UDPglucose 4-Epimerase