Article
Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis.
Molecular microbiology - 1 Aug 1998
Jennings M P, Virji M, Evans D, Foster V, Srikhanta Y N, Steeghs L, van der Ley P, Moxon E R
Abstract excerpt
The pili of Neisseria meningitidis are a key virulence factor, being major adhesins of this capsulate organism that contribute to specificity for the human host. Recently it has been reported that meningococcal pili are post-translationally modified by the addition of an O-linked trisaccharide, Gal (beta1-4) Gal (alpha1-3) 2,4-diacetimido-2,4,6-trideoxyhexose. Using a set of random genomic sequences from N....
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