Article
Identification of a novel gene involved in pilin glycosylation in Neisseria meningitidis.
Molecular microbiology - 1 Aug 1998
Jennings M P, Virji M, Evans D, Foster V, Srikhanta Y N, Steeghs L, van der Ley P, Moxon E R
Abstract excerpt
The pili of Neisseria meningitidis are a key virulence factor, being major adhesins of this capsulate organism that contribute to specificity for the human host. Recently it has been reported that meningococcal pili are post-translationally modified by the addition of an O-linked trisaccharide, G...
Topics
- Amino Acid Sequence
- Antibodies
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Base Sequence
- Carbohydrate Sequence
- Cells, Cultured
- Cloning, Molecular
- DNA Primers
- DNA, Bacterial
- Fimbriae Proteins
- Genes, Bacterial
- Glycosylation
- Glycosyltransferases
- Humans
- Molecular Sequence Data
- Mutation
- Neisseria meningitidis