Article

Comparative genomics of two sequential <i>Candida glabrata</i> clinical isolates

2017-04-30

Abstract excerpt

Candida glabrata is an important fungal pathogen which develops rapidly antifungal resistance in treated patients. It is known that azole treatments lead to antifungal resistance in this fungal species and that multidrug efflux transporters are involved in this process. Specific mutations in the transcriptional regulator PDR1 result in upregulation of the transporters. In addition, we showed that the PDR1 mutati...

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Literature Corpus work: 3071668f-bafa-5ac7-920b-f32e9e6fb690
DOI: 10.1101/132464

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