Article

Bayesian-frequentist hybrid inference framework for single cell RNA-seq analyses

2023-10-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Single cell RNA sequencing technology (scRNA-seq) has been proven useful in understanding cell-specific disease mechanisms. However, identifying genes of interest remains a key challenge. Pseudo-bulk methods that pool scRNA-seq counts in the same biological replicates have been commonly used to identify differentially expressed genes. However, such methods may l...

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Literature Corpus work: ffcd539b-dd53-5224-9bcb-d17234b1df14
DOI: 10.21203/rs.3.rs-3384541/v1

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