Article

Spatio-temporal dynamics of growth and death within spherical bacterial colonies

2021-04-27

Abstract excerpt

Bacterial growth within colonies and biofilms is heterogeneous. Local reduction of growth rates has been associated with tolerance against various antibiotics. However, spatial gradients of growth rates are poorly characterized in three-dimensional bacterial colonies. Here, we report two spatially resolved methods for measuring growth rates in bacterial colonies. As bacteria grow and divide, they generate a veloci...

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Literature Corpus work: ffbe3683-7555-5726-8933-71f3985edb21
DOI: 10.1101/2021.04.27.441609

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