Article
Computational model of fractal interface formation in bacterial biofilms.
Physical review. E - 1 Dec 2025
Brooks Caelan, Yao Meiyi, McCool Jake T, Gillman Alan, Süel Gürol M, Mugler Andrew, Larkin Joseph W
Abstract excerpt
Bacteria benefit from cellular heterogeneity: cells differentiate into diverse gene expression states. As colonies grow, cellular phenotypes arrange into spatial patterns. To uncover the functional role of these emergent patterns, we must understand how they arise from cellular growth and mechanical interactions. Here we present a simple, agent-based model to predict patterns of motile and extracellular...
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