Article

RT-PCR/MALDI-TOF diagnostic target performance reflects circulating SARS-CoV-2 variant diversity in New York City

2021-12-07

Abstract excerpt

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate, multiple variants of concern (VOC) have emerged. New variants pose challenges for diagnostic platforms since sequence diversity can alter primer/probe binding sites (PBS), causing false-negative results. The Agena MassARRAY ® SARS-CoV-2 Panel utilizes reverse-transcription polymerase chain reaction and mass-spectrometry to dete...

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Literature Corpus work: fed5cca4-d99f-581f-9f2d-97feb35c95f7
DOI: 10.1101/2021.12.04.21267265

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