Article

Quantitative imaging of gene therapy delivery vehicles using CEST-NMR/MRI

2022-11-10

Abstract excerpt

<h4>Purpose</h4> Gene therapy employing AAV vector-mediated gene delivery has undergone substantial growth in recent years with promising results in both preclinical and clinical studies, as well as emerging regulatory approval. However, the lack of methods for quantifying the efficacy of gene therapy from cellular delivery of gene editing technology to specific functional outcomes remains an obstacle for the eff...

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Literature Corpus work: fed02357-3df5-5ec3-b706-3e5b42821fa8
DOI: 10.1101/2022.11.09.515733

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