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Transcriptome of plasma exosome identifies a hsa-miR-483-5p/mRNAs network that regulates chemotherapy resistance in locally advanced rectal cancer

2024-01-19

Abstract excerpt

Chemoresistance is a primary contributor to distant metastasis in the context of neoadjuvant chemoradiotherapy (nCRT) in rectal cancer, the underlying mechanisms remain elusive. In this study, the profiles of plasma exosome miRNAs were compared in two dimensions according to treatment responses (poor/well-responders) and treatment courses (pre/post-nCRT) by RNA-sequencing. The exosome hsa-miR-483-5p was up-regulat...

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Literature Corpus work
fe6aca6c-12ae-5c61-be24-dc3c2997ffd8
DOI
10.21203/rs.3.rs-3866954/v1
Open publication

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Transcriptome of plasma exosome identifies a hsa-miR-483-5p/mRNAs network that regulates chemotherapy resistance in locally advanced rectal cancerDOI 10.21203/rs.3.rs-3866954/v1
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