Article

A proteogenomic RNA processing mechanism drives sex differences in meningioma

2026-06-02

Abstract excerpt

<title>Abstract</title> <p>Meningiomas are the most common primary intracranial tumors and the only brain tumors that are more common in females compared with males1. Progestin hormonal therapies increase the risk of meningioma, and progestin-induced or pregnancy-associated meningiomas can regress as serum progestogen levels normalize2. The mechanisms that underlie sex differences and progestogen signaling in men...

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Literature Corpus work: fe3d862a-ef60-52ea-91dc-adc58b9cc66f
DOI: 10.21203/rs.3.rs-9675139/v1

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