Meningiomas: Sex-specific differences and prognostic implications of a chromosome X loss

Abstract excerpt

BACKGROUND: Meningiomas are the most common primary intracranial tumors in adults. Several studies proposed new stratification systems with a more accurate risk prediction than the WHO grading, eg, based on methylation and copy-number variations (CNVs). Yet, common shortcomings in these analyses are either a lack of stratification by sex of patients or excluding the gonosomes from CNV assessment. METHODS: Within...

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