Article

SUMO chains depolymerization induces slender to stumpy differentiation in <i>T. brucei</i> bloodstream parasites

2023-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Trypanosoma brucei are extracellular protozoan parasites transmitted by tsetse flies that cause sleeping sickness in humans and nagana in cattle. Inside the mammalian host, differentiation from a bloodstream replicative slender form into a quiescent stumpy form allows the persistence of the parasite and the spread of the infection. SUMOylation is a reversible and dynamic post-translational modif...

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Literature Corpus work: fe0c0d04-7b5e-5638-b54c-423cbb07cdd6
DOI: 10.1101/2023.11.15.567218

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