Article
SUMO polymeric chains are involved in nuclear foci formation and chromatin organization in Trypanosoma brucei procyclic forms.
PloS one - 1 Jan 2018
Iribarren Paula Ana, Di Marzio Lucía Ayelén, Berazategui María Agustina, De Gaudenzi Javier Gerardo, Alvarez Vanina Eder
Abstract excerpt
SUMOylation is a post-translational modification conserved in eukaryotic organisms that involves the covalent attachment of the small ubiquitin-like protein SUMO to internal lysine residues in target proteins. This tag usually alters the interaction surface of the modified protein and can be translated into changes in its biological activity, stability or subcellular localization, among other possible outputs....
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