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A new method based on the von Mises-Fisher distribution shows that a minority of liver-localized CD8 T cells display hard-to-detect attraction to <i>Plasmodium</i> -infected hepatocytes

2020-12-12

Abstract excerpt

Malaria is a disease caused by Plasmodium parasites, resulting in over 200 million infections and 400,000 deaths every year. A critical step of malaria infection is when sporozoites, injected by mosquitoes, travel to the liver and form liver stages. Malaria vaccine candidates which induce large numbers of malaria-specific CD8 T cells in mice are able to eliminate all liver stages, preventing fulminant malaria. Ho...

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Literature Corpus work
fe06c926-e03e-508e-9c33-5c85f930a9b0
DOI
10.1101/2020.12.12.422451
Open publication

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A new method based on the von Mises-Fisher distribution shows that a minority of liver-localized CD8 T cells display hard-to-detect attraction to <i>Plasmodium</i> -infected hepatocytesDOI 10.1101/2020.12.12.422451
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