Competitive resource allocation drives asynchronous and rapid nuclear multiplication in the malaria parasite

Abstract excerpt

The unicellular malaria parasite Plasmodium falciparum proliferates within the red blood cells of its human host, where it generates approximately 20 new parasites within an infection cycle of two days. Proliferation proceeds by nuclear divisions in a shared cytoplasm, followed by cellularization. In stark contrast to the highly synchronized nuclear division cycles in many eukaryotes, Plasmodium nuclear cycles d...

Topics

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• Drug Transport and Resistance Mechanisms
• HIV/AIDS drug development and treatment
• HIV Research and Treatment
• Invertebrate Immune Response Mechanisms
• Malaria Research and Control
• Microtubule and mitosis dynamics
• Mosquito-borne diseases and control
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

626453f7-92d9-5d4c-b3e8-6d048bd6dc34

DOI

10.1101/2025.08.07.669072