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Article

Caspase-dependent apoptosis in Riboflavin Transporter Deficiency iPSCs and derived motor neurons

2023-06-29

Abstract excerpt

<title>Abstract</title> <p>Riboflavin Transporter Deficiency (RTD) is a rare genetic, childhood-onset disease. This pathology has a relevant neurological involvement, being characterized by motor symptoms, ponto-bulbar paralysis and sensorineural deafness. Such clinical presentation is associated with muscle weakness and motor neuron (MN) degeneration, so that RTD is considered part of the MN disease spectrum. Ba...

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Literature Corpus work
fd4e669e-9226-5914-a548-f192ec8e7e1a
DOI
10.21203/rs.3.rs-3062721/v1
Open publication

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