Evolution of Nitrogen-Based Alkylating Anticancer Agents

Abstract excerpt

Despite the significant progress in anticancer drug development over recent years, there is a vital need for newer agents with unique, but still effective, mechanisms of action in order to treat the disease, particularly the highly aggressive and drug-resistant types. Alkylating agents, in particular nitrogen-based alkylators, are commonly used to treat hematological and solid malignancies; they exert their antine...

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Literature Corpus work

fcdda27c-0e5d-5497-a424-acf37f379f4f

DOI

10.3390/pr9020377