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Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities

15 Jul 2023

Abstract excerpt

Cytotoxic chemotherapy remains a key modality in cancer treatment. These therapies, successfully used for decades, continue to transform the lives of cancer patients daily. With the high attrition rate of current oncology drug development, combined with the knowledge that most new therapies do not displace standard-of-care treatments and that many healthcare systems cannot afford these new therapies; cytotoxic...

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PMID: 37452860
DOI: 10.1007/s00280-023-04562-3

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